APEX Ipamorelin, CJC-1295 10MG / 10MG Blend (no DAC)

APEX Ipamorelin and CJC-1295 no DAC (Mod GRF 1-29) are synthetic research peptides used together in experimental models to study growth hormone axis regulation and pituitary signaling dynamics. Ipamorelin is a selective pentapeptide growth hormone secretagogue that acts as an agonist of the growth hormone secretagogue receptor (GHS-R1a), activating Gq/PLC and calcium-dependent signaling pathways involved in GH release while exhibiting minimal interaction with other pituitary hormones in preclinical systems. CJC-1295 no DAC is a stabilized analog of growth hormone–releasing hormone (GHRH 1-29) that activates the GHRH receptor, stimulating adenylate cyclase and cAMP-mediated signaling in somatotroph cells. Preclinical research employs the combined activation of GHS-R1a and GHRH receptors to investigate synergistic somatotropic signaling, hypothalamic–pituitary feedback mechanisms, and peptide-mediated endocrine regulation. 

For research use only. Not for human consumption. 

References: Bowers CY et al., Ann NY Acad Sci, 1998 865:244–249

 Frohman LA et al., Endocr Rev, 2001 22(6):606–648 

Svensson J et al., J Endocrinol Invest, 1998 21(9):692–699

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For Research Use Only (RUO).Not for human or veterinary use.Not intended for diagnosis, treatment, cure, or prevention of any disease.

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